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Medical & Health Collection
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Acceptable use information
What's OK:
If you have permission to use this library, you may use the images
1) in presentations (computer-generated or slides) or
2) on posters (one print only, of any one image). Please credit the CBE and the source noted.
What's not OK:
To submit any of these images for print reproduction (the quality is not adequate anyway!) or to make multiple copies for distribution without express
written permission from the source and CBE.
How to acquire images
1. Click on the image you want to use – you will be linked to a full-sized (11" x 7.33") version of the
image.
2. Right-click on the image and select "Copy" from the dialogue box that appears.
3. Open a presentation in PowerPoint. Make sure that page set-up is for 35mm slides. Select page you want the image on. From the
edit menu, select "Paste." Voila!
If you have questions, contact Peg Dirckx.
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Filename
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Alveoli_A_11-04.jpg | |
JPG filesize
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54 K
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Date
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2004 | |
Source
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Bill Costerton / Peg Dirckx | |
Description
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In addition to oxygen/carbon dioxide exchange, the
human lungs are effective “scrubbers”— eliminating inhaled microbes. In the tiny
alveoli sacs of the lung, single microbes are quickly ingested by activated
neutrophils. | |
Keywords
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lung infection, neutrophil response |
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Filename
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Alveoli_B_11-04.jpg | |
JPG filesize
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62 K
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Date
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2004 | |
Source
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Bill Costerton, Mike Franklin / Peg Dirckx | |
Description
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When the immune response is compromised, bacteria
are able to colonize the alveoli, and to form biofilms. Biofilms do not trigger
the neutrophils to become activated, even in the presence of antibodies (yellow
symbols). When biofilm cells are released from the community singly, they are
readily “recognized” and ingested by neutrophils. | |
Keywords
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lung infection, neutrophil response, cystic fibrosis |
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Filename
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Alveoli_C_11-04.jpg | |
JPG filesize
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69 K
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Date
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2004 | |
Source
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Bill Costerton, Mike Franklin / Peg Dirckx | |
Description
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Studies of neutrophil / biofilm interactions in
Pseudomonas aeruginosa biofilms have shown that neutrophils retain their
basic un-activated round shape—becoming only minimally active—and settle into
the biofilms, releasing a “cloud” of single cells. A well-established biofilm
will grow thicker over time, and may calcify (white areas), rendering the
alveolus inactive. | |
Keywords
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lung infection, neutrophil response, cystic fibrosis |
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Filename
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CBE99_DentInflam.jpg | |
JPG filesize
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86 K
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Date
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1999 | |
Source
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Bill Costerton / Kathy Lange
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Description
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Hundreds of microbial species colonize the human mouth. Some species are
pathogenic, and can cause infection, tooth decay and gum disease. | |
Keywords
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health, dental
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Filename
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CBE99-TamponInf.jpg | |
JPG filesize
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64 K
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Date
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1999 | |
Source
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Bill Costerton / Kathy Lange, Peg Dirckx | |
Description
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Microbes that colonize vaginal tissue and tampon fibers can become pathogenic,
causing inflammation and disease such as Toxic Shock Syndrome. | |
Keywords
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health, infection |
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Filename
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CBE03_1n2infect.jpg | |
JPG filesize
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134 K
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Date
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2003 | |
Source
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Paul Stoodley, Dr. Christoph Fux / Peg Dirckx | |
Description
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Three examples of the many possible points of entry for bacteria are shown here,
along with common areas of secondary infection (highlighted in green). Once
bacteria enter the circulatory system, they can reach all parts of the body. | |
Keywords
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health, infection |
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214597wb.jpg
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Filename
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214597wb.jpg
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JPG filesize
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116 K
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Date
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1997
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Source
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Bill Costerton / Peg Dirckx
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Description
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Attachment blockers and detachment signals can be used to prevent cells of periodontal pathogens (Fusobacterium nucleatum) from joining the biofilm on teeth.
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Keywords
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cell-cell_communication, signaling, health, dental
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237398_wb.jpg
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Filename
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2373_98wb.jpg
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JPG filesize
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76 K
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Date
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1998
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Source
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Bill Costerton / Peg Dirckx
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Description
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Cells of Staphylococcus epidermidis grow in a biofilm on the sewing cuff at a mechanical heart valve and cause devastating disease.
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Keywords
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cell-cell_communication, signaling, medical_health, heart, cardiac
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2374_98wb.jpg
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Filename
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2374_98wb.jpg
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JPG filesize
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98 K
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Date
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1998
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Source
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Bill Costerton / Peg Dirckx
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Description
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Biofilm cells on the sewing cuff are removed, as planktonic cells, by the activity of a "locking" analogue of the specific detachment signal.
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Keywords
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cell-cell_communication, signaling, detachment, medical_health, heart, cardiac
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2393_98wb.jpg
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Filename
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2393_98wb.jpg
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JPG filesize
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128 K
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Date
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1998
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Source
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Bill Costerton / Kathy Lange
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Description
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Planktonic bacterial cells are susceptible to antibiotics, antibodies, and phagocytes. Biofilm cells are highly protected from all three antibacterial agents.
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Keywords
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medical_health, resistance
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