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Center for Biofilm Engineering
News Update:
October, 2008
Volume 11, Issue 10
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Research Highlights
Recent Awards
Metabolic Engineering
Ross Carlson, Assistant Professor, Chemical & Biological
Engineering, received an award from Idaho National Laboratory for a
3-year $90,000 grant titled “Metabolic engineering of
Alicyclobacillus acidocaldarius for lactic acid production from
biomass.” Alicyclobacillus acidocaldarius is an acid
tolerant, thermophilic microorganism isolated from a Yellowstone
National Park hot spring. The organism is being explored to
determine if it is suitable for making lactic acid, a precursor for
a biodegradable plastic, from cheap biomass substrates like
agricultural waste. The project began June 4, 2008.
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MRSA Biofilms
Columbia Biosystems has
awarded Garth James, Associate Research Professor and Medical
Projects Manager, a 1-year $142,023 grant titled “Determination of
proteins and peptides unique to MRSA biofilms.” The research will
focus on the identification of target molecules for detecting MRSA
biofilms. The project began September 22, 2008.
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Montana Board of Research and Commercialization Technology
Awards
The Montana Board of Research and Commercialization Technology
has given the CBE three awards for the research described below.
Darla Goeres, Assistant Research Professor, Chemical & Biological
Engineering, was awarded a 2-year $133,970 grant titled “Research
support for standardizing comprehensive biofilm efficacy test
system.” The funding will support the design and testing of a
research tool that will be manufactured and sold by BioSurface
Technologies Inc. The research will be done in collaboration with
students from the Department of Mechanical and Industrial
Engineering under the direction of Mr. Kevin Cook.
The project began
September 1, 2008.
Alfred Cunningham, Professor, Civil Engineering and Anne Camper,
Professor, Civil Engineering, were awarded a 2-year $250,316 grant
titled “Control of microbial processes for enhanced water treatment
using floating island treatment systems.” The project’s goal is to
conduct research on the dynamics of microbial communities occurring
in engineered floating islands used for water treatment. These
floating islands (trademarked BiohavenTM), which consist
of a non-woven matrix made of 100% recycled plastic fabricated into
floating mats, have been developed by Floating Island International,
Inc. The project began
August 1, 2008.
Philip Stewart, CBE Director, was awarded a 1-year $100,470 grant
titled “Development of bismuth-thiol based therapeutic agents for
treating chronic wounds.” This proposal is a partnership between
Microbion Corporation and MSU-CBE to develop a topical
anti-infective, anti-biofilm drug formulation for the treatment of
chronic wounds. The type of wounds that will be specifically
targeted by this technology includes diabetic foot ulcers and venous
leg ulcers that are notoriously difficult or impossible to heal, and
can lead to amputation. The
project began July 1, 2008.
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Outreach
Visitors
Claudia Doberenz is visiting the
CBE for nine months on a Fulbright fellowship from Germany,
where she earned a MS degree in microbiology from Martin Luther
University in Halle/Wittenberg. She is here as a non-degree
graduate student, working in the Industrial & Environmental Water
Systems lab as part of her Fulbright fellowship experience. She will
be looking at interspecies competition in a biofilm. Claudia will
return to Germany to complete her PhD.
Dr. Peter Gostomski, head of the Department of
Chemical and Process Engineering, University of Canterbury,
Christchurch, New Zealand, visited the CBE September 29, 2008. He
toured the CBE and met with Brent Peyton.
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Education
Fellowship Award
Crystal Richards, PhD candidate in Microbiology, and
faculty sponsor Anne Camper received a 3-year EPA STAR (Science to
Achieve Results) Graduate Fellowship, beginning August 5, 2008.
Congratulations, Crystal!
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Montana
INBRE Program
Kara Bowen and Kelly O’Shea,
as part of the Montana INBRE Program (IDeA Network of Biomedical
Research Excellence), attended the Pathways into Health Conference
in Girdwood, Alaska, September 8−10,
2008. The conference covered education of Native Americans in
health professions. INBRE invited Kara and Kelly to attend as
representatives since they do heavy-metal contamination work and
could contribute to discussions.
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Thesis Alert
“Proteomic and transcriptomic analyses reveal genes upregulated by
cis-dichloroethene in Polaromonas JS666,” thesis
defense by Laura Jennings, visiting PhD candidate in Environmental
Engineering, Cornell University, Ithaca, New York, and Visiting
Researcher at the CBE, Montana State University, September 2008
“Physiological analysis of Desulfovibrio
vulgaris Hildenborough under conditions relevant to the
subsurface environment: Carbon and energy limitation and biofilm
formation,” thesis defense by Melinda Clark PhD candidate in
Microbiology, Miami University, Oxford, Ohio, and Visiting
Researcher at the CBE, Montana State University, August 2008
View thesis abstracts
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CBE People in Action
Phil Stewart as an invited
speaker will present “Antimicrobial tolerance in staphylococcal
biofilms,” at the 48th Annual ICAAC/IDSA 46th Annual Meeting,
Washington, DC, October 25−28,
2008.
Garth James will present
"Prevention of S. aureus biofilm in vitro using
5-FU-coated central venous catheters" at the 48th Annual ICAAC/IDSA
46th Annual Meeting, Washington, DC, October 25−28,
2008. Authors: GA James, S Fisher, SF Rosebrough, and JE Perry.
Christine Foreman presented
two talks: “Impact of climate change on polar organisms,” “Stories
from a changing planet” as well as teacher workshops at the Society
for Advancement of Chicanos and Native Americans in Science, Salt
Lake City, UT October 9−12,
2008.
Mervin Failing, a Bridging
Tribal College Student to MSU (summer program) received the Best
Poster award for “Response of bacteria to freezing,” at the Society
for Advancement of Chicanos and Native Americans in Science, Salt
Lake City, UT, October 9−12,
2008. Mervin is a student at Ft. Peck Community College, MT,
majoring in education. For his efforts, Mervin received a
certificate and $500. Poster co-authors: Mervin Failing, Markus
Dieser, Betsey Pitts, and Christine Foreman.
Phil Stewart presented
“Visualization of antimicrobial action in Staphylococcus
epidermidis biofilms” at the International Biofilms III
Conference in Munich, Germany, October 4−9,
2008.
Christine Foreman presented the poster “DOC, microbial abundance
and activity in the Upper WAIS Divide Core” at the annual science
meeting for the West Antarctic Ice Sheet Divide Project, Denver, CO,
September 30–October 2,
2008. Poster co-authors: Christine M. Foreman, Joe McConnell and
John C. Priscu.
Phil Stewart presented
“Alternative strategies for biofilm control” at a workshop focusing
on biofilms and biocorrosion, sponsored by the Army Research Office,
on September 22, 2008, Dallas, TX.
Matthew Fields presented
“Biodiversity and spatial dynamics of an engineered subsurface
environment” at the MicroEnGen-IV: 4th SCOPE Workshop on Microbial
Environmental Genomics, Central South University, Changsha, China,
September 17−24,
2008.
Christine Foreman lectured at
the Museum of Natural History in Cleveland, OH, September 12−13,
2008. She presented “Polar Palooza: Stories from a changing
planet” and a hands-on-children’s activity “A celebration of polar
research,” as part of the Explorer’s Lecture Series.
Zbigniew
Lewandowski participated in several significant activities at the
IWA Water Congress, Vienna, Austria, September 8−12,
2008.
He chaired the session “Biofilm
Processes,” and presented a paper
“Characterizing temporal
development of biofilm porosity using artificial neural networks.”
This paper has been published as “Characterizing temporal
development of biofilm porosity using artificial neural networks,”
Angathevar Veluchamy RR, Beyenal H, Lewandowski Z, Water Science and
Technology 57:1867–1872, 2008.
He
also chaired the meeting of the IWA Biofilm Specialist Group.
Working together with
the chairmen of two other specialist groups, (1) Water Reuse and (2)
Membrane Technology, Zbigniew helped organized a workshop,
“Biofouling of Membranes for Water and Wastewater.” He presented ““Mechanisms
of biofilm processes,” for the workshop.”
He
also participated in the meeting of the organizing committee of the
Biofilm Reactors Conference. It will be organized jointly by the
Water Environment Federation (WEF) and the International Water
Association (IWA). The conference is scheduled for 2010.
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Diane Williams
(editor) and Carol Leist (copy editor) of the CBE News Update.
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