Center for Biofilm Engineering
Abstract:
"Cystic Fibrosis Pathogenesis and the Role of Biofilms in Persistent
Infection"
01-001 Recent work has presented definitive evidence that the Pseudomonas
cells that infect the lung in cystic fibrosis grow in the biofilm
phenotype. These unequivocal data establish this chronic infection of
compromised hosts as the archetypal biofilm infection, which is both refractory
to antibiotic therapy and barely affected by host defenses.
Costerton, J.W., "Cystic Fibrosis Pathogenesis and the Role of Biofilms
in Persistent Infection," Trends in Microbiol., 9(2):50-52 (2001).
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