Center for Biofilm Engineering
Abstract:
"Gatifloxacin Efficacy in Treatment of Experimental Methicillin-Sensitive
Staphylococcus aureus-Induced Osteomyelitis in Rabbits"
02-003 The effectiveness of oral gatifloxacin was compared to that of standard parenteral antibiotic therapy (nafcillin) for the treatment of experimental methicillin-sensitive
Staphylococcus aureus-induced osteomyelitis in a rabbit model. Gatifloxacin was as effective as nafcillin in clearing the infection. Therefore, oral gatifloxacin treatment of osteomyelitis may be an effective alternative to intravenous nafcillin treatment.
Shirtliff, M.E., J.H. Calhoun, and J.T. Mader, "Gatifloxacin Efficacy in
Treatment of Experimental Methicillin-Sensitive Staphylococcus aureus-Induced
Osteomyelitis in Rabbits," Antimicrobial Agents and Chemotherapy,
46(1):231-233 (2002).
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