Center for Biofilm Engineering
Abstract:
"Penetration of Rifampin through Staphylococcus epidermidis
Biofilms"
02-010 Rifampin penetrated biofilms formed by Staphylococcus
epidermidis but failed to effectively kill the bacteria. Penetration
was demonstrated by a simple diffusion cell bioassay and by transmission
electron microscopic observation of antibiotic-affected cells at the distal edge
of the biofilm.
Zheng, Z. and P.S. Stewart, "Penetration of Rifampin through Staphylococcus epidermidis
Biofilms," Antimicrobial Agents and Chemotherapy, 46(3):900-903
(2002).
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